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刘婷姣教授简介
研究队伍
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研究成果

一、期刊论文

2017:

  1. Shimeng Fang, Hongzhu Tian, Xiancheng Li, Dong Jin, Xiaojie Li, Jing Kong, Chun Yang, Xuesong Yang, Yao Lu, Yong Luo, Bingcheng Lin, Weidong Niu*, Tingjiao Liu *. Clinical application of a microfluidic chip for immunocapture and quantification of circulating exosomes to assist breast cancer diagnosis and molecular classification. PLOS One. 2017 Accepted

  2. Xue Liu#, Jiujiao Gao, Yan Sun, Dandan Zhang, Tingjiao Liu, Qiu Yan*, Xuesong Yang*. Mutation of N-linked glycosylation in EpCAM affected cell adhension in breast cancer cells. Biological Chemistry. 2017 Mar 18. pii: /j/bchm.just-accepted/hsz-2016-0232/hsz-2016-0232.xml. doi: 10.1515/hsz-2016-0232. [Epub ahead of print]

  3. Dandan Zhang#, Xue Liu, Jiujiao Gao, Yan Sun, Tingjiao Liu, Qiu Yan*, Xuesong Yang*. The role of EpCAM N-glycosylation on apoptosis in breast cancer cells. Tumor Biology. 2017 Accepted

2016

  1. Kong J, Luo Y, Jin D, An F, Zhang W, Liu L, Li J, Fang S, Li X, Yang X, Lin B*, Liu T*. A multiple-organ-chip can mimic the organ-specific metastasis of circulating tumor cells in animals. Oncotarget. 2016;7(48):78421-78432

  2. Liu L, Xie Z, Zhang W, Fang S, Kong J, Jin D, Li J, Li X, Yang X, Luo Y, Lin B, Liu T*. Biomimetic tumor-induced angiogenesis and anti-angiogenic therapy in a microfluidic model. RSC Advances, 2016;6 (42), 35248-35256

  3. Jin D, Ma X, Luo Y, Fang S, Xie Z, Li X, Qi D, Zhang F, Kong J, Li J, Lin B*, Liu T*. Application of a microfluidic-based perivascular tumor model for testing drug sensitivity in head and neck cancers and toxicity in endothelium. RSC Advances, 2016;6 (35), 29598 - 29607

  4. Li J, Jia Zhu, Kong J, Zhang F, Fang S, Li X, Li W, Yang X, Luo Y, Lin B, Liu T*. Carcinoma-associated fibroblasts lead the invasion of salivary gland adenoid cystic carcinoma cells by creating an invasive track. PLOS One, 2016;11(3): e0150247

Before 2015:

  1. Li X, Shi Z, Wang Y, Liu Y, Liu T*. Immunohistochemical expression of cytokeratins in human salivary gland acinic cell carcinomas. Oral Surgery Oral Medicine Oral Pathology Oral Radiology. 2015; 120(2): 248-257

  2. Guan H, Tan J, Zhang F, Gao L, Bai L, Qi D, Dong H, Zhu L, Li X, Liu T*. Myofibroblasts from salivary gland adenoid cystic carcinomas promote cancer invasion by MMP2 and CXCL12. Histopathology. 2015, 66(6):781-790

  3. Gao J, Liu X, Yang F, Liu T, Yan Q, Yang X. By inhibiting Ras/Raf/ERK and MMP-9, knockdown of EpCAM inhibits breast cancer cell growth and metastasis. Oncotarget. 2015;6(29):27187-98

  4. Yu W, Qu H, Hu G, Zhang Q, Song K, Guan H, Liu T*, Qin J*. A microfluidic-based multi-shear device for investigating the effects of low fluid-induced stresses on osteoblasts. PLoS One. 2014;9(2):e89966

  5. Li W, Tamamura R, Wang B, Liu Q, Liu H, Liu T, Katase N, Xiao J, Nagatsuka H. Expressions of ABCG2, CD133, and podoplanin in salivary adenoid cystic carcinoma. Biomed Res Int. 2014;2014:132349.

  6. Zhang Q, Liu T*, Qin J*. A microfluidic-based device for study of transendothelial invasion of tumor aggregates in realtime. Lab chip. 2012, 12(16), 2837–42

  7. Liu W, Zhu E, Wang R, Wang L, Liu T*. CXCL12 G801A polymorphism is associated with an increased risk of benign salivary gland tumors in the Chinese population. Med Oncol. 2012;29(2):677-81.

  8. Liu W, Zhu E, Wang R, Wang L, Gao L, Yang X, Liu T*. Cyclin D1 gene polymorphism, A870G, is associated with an increased risk of salivary gland tumors in the Chinese population. Cancer Epidemiol. 2011,35(4):e12-7.

  9. Liu T, Lin B and Qin J. Carcinoma-associated fibroblasts promoted tumor spheroid invasion on a microfluidic 3D co-culture device. Lab Chip. 2010, 10(13), 1671-7

  10. Ma H, Liu T, Lin B and Qin J. Characterization of the interaction between fibroblasts and tumor cells on a microfluidic co-culture device. Electrophoresis. 2010;31(10):1599-605

  11. Yang X, Liu S, Liu Y, Liu J, Liu T, Wang X, Yan Q. Overexpression of fucosyltransferase IV promotes A431 cell proliferation through activating MAPK and PI3K/Akt signaling pathways. J Cell Physiol. 2010, 225(2):612-9

  12. Liu T, Li C, Li H, Zeng S, Qin J, Lin B. A microfluidic device for characterizing the invasion of cancer cells in 3-D matrix. Electrophoresis. 2009, 30 (24): 4285-91

  13. Kadouchi I, Sakamoto K, Liu T, Murakami T, Kobayashi E, Hoshino Y, Yamaguchi A. Chondrocyte differentiation Latexin is involved in bone morphogenetic protein-2-induced. Biochem Biophys Res Commun. 2009, 378:600–4

  14. Liu T, Gao Y, Sakamoto K, Miminazato M, Furukawa K, Tsukazaki T, Shibata Y, Bessho K, Komori T, Yamaguchi A. BMP-2 promotes differentiation of osteoblasts and chondroblasts in Runx2-deficient cell lines. J Cell Physiol. 2007, 211 (3):728-35

  15. Minamizato T, Sakamoto K, Liu T, Kokubo H, Katsube K, Perbal B, Nakamura S, Yamaguchi A. CCN3/NOV inhibits BMP-2-induced osteoblast differentiation by interacting with BMP and Notch signaling pathways. Biochem Biophys Res Commun. 2007, 354:567-73

  16. Wang L, Liu T, Wang Y, Cao L, Nishioka M, Aguirre RL, Ishikawa A, Geng L, Okada N. Altered expression of desmocollin 3, desmoglein 3, and beta-catenin in oral squamous cell carcinoma: correlation with lymph node metastasis and cell proliferation. Virchows Arch. 2007, 451(5):959-66

  17. Wang L, Liu T, Nishioka M, Aguirre RL, Win SS, Okada N. Activation of ERK1/2 and cyclin D1 expression in oral tongue squamous cell carcinomas: relationship between clinicopathological appearances and cell proliferation. Oral Oncol. 2006, 42(6):625-31

  18. Liu T, Zhu E, Wang L, Okada Y, Yamaguchi A, Okada N. Abnormal expression of Rb pathway-related proteins in salivary gland acinic cell carcinoma. Hum Pathol. 2005, 36 (9): 962-70

二、授权专利

  1. 一种微流控芯片及其研究肿瘤细胞团外渗的方法;授权号:zl 201110151866.9;发明专利;发明人:刘婷姣,张茜,秦建华,林炳承;授权时间2014年6月18日;授权国别,中国

  2. 一种微流控芯片及其研究流体剪切力对细胞作用的方法;授权号:zl 201110151905.5;发明专利;发明人:刘婷姣,虞炜亮,秦建华,林炳承;授权时间 2014年1月22日年;授权国别,中国

  3. 一种微流控芯片及其应用;授权号:zl 200910220069.4;发明专利; 发明人:秦建华,刘婷姣,林炳承;授权时间 2013年12月4日;授权国别,中国

  4. 一种多维多浓度药敏检测微流控芯片;授权号:zl 201420262631.6,实用新型专利;发明人:刘婷姣,金冬,林炳承,罗勇;授权时间:2015年1月14日

三、科研获奖

  1. 口腔颌面部肿瘤与发育畸形的基础和临床研究,辽宁省科技进步二等奖,2012年8月, 2012J-2-69-03

  2. 细胞周期素D1对口腔颌面部肿瘤发生及预后的影响,辽宁省级科技进步三等奖,2013年,证书编号:2013J-3-115-01

  3. 细胞周期素D1对口腔颌面部肿瘤发生及预后的影响,大连市科技进步二等奖,2012年8月,2011J-2-19-01

  4. 先天性唇腭裂发生机制与缺损修复的系列研究,大连市科技进步一等奖,2012年8月, 2011J-1-11-04

  5. 先天性唇腭裂发生机制与缺损修复的系列研究,辽宁省级科技进步三等奖,2013年,证书编号:2013J-3-114-04

  6. 中药药效物质与代谢属性明晰在指导中药合理使用中的应用.教育部2016年度高等学校科学研究优秀成果奖(科学技术). 科技进步二等奖. 马骁驰,麻彤辉,张波,王寿宇,彭金咏,刘克辛,高建,姚继红,刘婷姣,王超,霍晓奎,刁云鹏,张琳,田象阁.



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